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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment choice for chronic weight management in addition to a reduced-calorie diet and physical activity.

Using two separate drugs to lose weight naturally can be very effective you will find combinations while watching FDA now awaiting approval. When dealing with weight loss and the individuals who go through it you should err on the side of caution and allow FDA do its job and demand some investigation be done so your public understands the side effects and risks of the medications before we bring them. Keep in mind that drug companies will be in business to make money and that they would say almost anything to keep people on their own medications.

Researchers found out that participants taking this drug for any year, lost excess weight within a month and have kept the extra weight off during the entire 56 weeks in the study. Contrave is really a combination in the drugs naltrexone and bupropion, which generally seems to reflect a whole new trend of weight-loss drugs which are made up of several active ingredient, which may make them far better and safer.

Combo-pilling may be the newest fad or better yet the newest in the future under scrutiny and so it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that using a combination of pills is starting to become popular will be the fact that as of right now there are not any long term prescription slimming capsules that have been authorized by the FDA apart from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications and some of the combinations have been rejected or have yet to be approved by the FDA.

Seizures really are a side effect with Contrave and really should not be taken in those with seizure disorders. The drug could also raise blood pressure and heartrate, and must not be used in individuals with a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise blood pressure level and heartrate and must 't be used in patients with uncontrolled high hypertension, in addition to by you aren't heart-related and cerebrovascular (circulatory dysfunction impacting mental performance) disease. Patients using a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes with a boxed warning to alert health care professionals and patients for the increased risk of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stop smoking.


A pyromaniac, with both psychiatric and medical therapy, can still be treated. It is best completed with behavioral therapy. Psychotherapy treatment alongside behavior modification is regarded as the frequently used treatment. Based on the study of Jon Grant, a mixture treatment of drugs and behavioral therapy is discovered to be successful in treating pyromania. The use of serotonin reuptake inhibitors is also beneficial in controlling the impulsive behavior from the patient like other impulse control disorder. Also helpful for the patient are medications like Lithium, naltrexone, (ReVia), fluoxetine (Prozac), citalopram (Celexa), paroxetene (Paxil), along with other antidepressants.
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